I take a lot of medications. How can I manage side effects and know there won’t be any interactions?

If you are concerned about the number of medications you take and any possible side effects, then you should speak to your health care provider about this. Your doctor knows about drug interactions and can help you with any side effects by either changing medications or by adjusting you medication dosages.
Although it may not be possible to avoid all possible side effects and drug interactions, it is nonetheless possible to minimize them. Today we have computer software and online recourses that help us detect possible drug interactions even for newer drugs or for less common drug interactions.